19th May 2012

Photoset reblogged from Jessica Capshaw. Sara Ramirez. That's all. with 2,367 notes

“Mark… Mark, hold on. I need you- I need you to hold on.”

Source: phoenixandlittlegrey

18th May 2012

Photoset reblogged from with 559 notes

okay.

Source: calzona-monster

18th May 2012

Photoset reblogged from Jessica Capshaw. Sara Ramirez. That's all. with 1,233 notes

Source: dammit-jerry

18th May 2012

Photo reblogged from The Voguette with 10,886 notes

Source: soufialakhdar

17th May 2012

Photoset reblogged from why happening with 4,499 notes

THANK YOU FOR 5 YEARS OF LEXIE GREY MEMORIES, CHYLER LEIGH!

Source: lexiecarolinegrey

15th May 2012

Photoset reblogged from with 8,292 notes

Source: lejazzhot

12th May 2012

Post reblogged from what? with 4 notes

lizzyourlife:

Taking Chances is one of the most underrated Rachel Berry solos in the whole show. 

AND MY MAN too

Source: lizzyourlife

6th May 2012

Photo reblogged from NeuroLove with 28 notes

neurolove:

This is an image of the myenteric plexus (helps control the digestive tract) with tyrosine hydroxylase labeled green through immunohistochemistry.  Tyrosine hydroxylase is the enzyme that converts tyrosine (an amino acid) to L-DOPA, the precursor for dopamine, norepinephrine (aka noradrenaline), and epinephrine (aka adrenaline), so the green is therefore labeling axons from the sympathetic autonomic nervous system (which helps regulate digestion, heartrate, breathing, etc.).  The blue is postganglionic neurons.  [image Source]

neurolove:

This is an image of the myenteric plexus (helps control the digestive tract) with tyrosine hydroxylase labeled green through immunohistochemistry.  Tyrosine hydroxylase is the enzyme that converts tyrosine (an amino acid) to L-DOPA, the precursor for dopamine, norepinephrine (aka noradrenaline), and epinephrine (aka adrenaline), so the green is therefore labeling axons from the sympathetic autonomic nervous system (which helps regulate digestion, heartrate, breathing, etc.).  The blue is postganglionic neurons.  [image Source]

Source: neurolove

6th May 2012

Photo reblogged from NeuroLove with 39 notes

neurolove:

These are slices through the midbrain (like a bread slice).  The black “lines” that you see are the substantia nigra (now I think you can tell why it’s called ‘black substance’).  The slice on the left is from a patient with Parkinson’s Disease.  The slice on the right is from a “normal” brain.  As you can see, Parkinson’s involves severe degradation of the neurons in the substantia nigra, resulting in the loss of dopamine to the brain.
From the last post, you know that dopamine promotes movement in both the direct and indirect pathways of the basal ganglia circuitry.  This means that when neurons of the substantia nigra die, that excitatory input is lost and so the basal ganglia indirect pathway is overactive and the direct pathway is underactive.  This is why Parkinson’s patients experience difficulty moving that progresses as the disease progresses and more of the dopaminergic neurons die.
[Image Source]

neurolove:

These are slices through the midbrain (like a bread slice).  The black “lines” that you see are the substantia nigra (now I think you can tell why it’s called ‘black substance’).  The slice on the left is from a patient with Parkinson’s Disease.  The slice on the right is from a “normal” brain.  As you can see, Parkinson’s involves severe degradation of the neurons in the substantia nigra, resulting in the loss of dopamine to the brain.

From the last post, you know that dopamine promotes movement in both the direct and indirect pathways of the basal ganglia circuitry.  This means that when neurons of the substantia nigra die, that excitatory input is lost and so the basal ganglia indirect pathway is overactive and the direct pathway is underactive.  This is why Parkinson’s patients experience difficulty moving that progresses as the disease progresses and more of the dopaminergic neurons die.

[Image Source]

Source: neurolove

6th May 2012

Photoset reblogged from Feelin' like a little kid with 156 notes

Source: desafiandolagravedad